Stop Approval of Animal Drug that Threatens Public Health!

Antibiotic resistance is a growing crisis in human medicine, and the use of important human drugs in animal agriculture unnecessarily places our health at risk. The Food and Drug Administration (FDA) is currently considering an application by drug company Schering-Plough to allow an antibiotic called cefquinome to be used to treat cattle respiratory infections. Cefquinome is from the class of drugs known as “fourth-generation cephalosporins”—drugs that are highly valued in human medicine to treat life-threatening infections. Widespread use of cefquinome in cattle could drive human bacterial resistance to this critical class of drugs.

Please sign this petition to Schering-Plough CEO Fred Hassan urging the company to withdraw its application for use of cefquinome in cattle.

Sample Letter for Campaign

Subject: Withdraw Schering-Plough's New Animal Drug Application for Cefquinome

Dear [ Decision Maker ] ,

Dear Fred Hassan:

We, the undersigned, urge Schering-Plough to withdraw its new animal drug application to the Food and Drug Administration (FDA) for the approval of cefquinome. Cefquinome and other 4th generation cephalosporins are critical for treating human disease and their use in animals would pose an unnecessary risk to their effectiveness.

In September 2006, an FDA advisory committee found that use of cefquinome in cattle was likely to contribute to bacterial resistance to this class of antibiotics in humans. Additionally, 14 other drugs are already approved for respiratory disease treatment in cattle. Given these facts, along with the strong consensus against approval among the public health community in the United States, I urge Schering-Plough to do the right thing and withdraw its application for cefquinome.

By withdrawing the cefquinome application, Schering-Plough would send a strong signal that the company is committed to protecting public health and to fulfilling its stated vision of earning trust.

Signed by:

Campaign Launched:
March 12, 2008



Background Information

Antibiotic resistance is a growing crisis in human medicine, and our health is put at unnecessary risk by the use of important human drugs in animal agriculture. The Food and Drug Administration (FDA) is currently considering an application by drug company Schering-Plough to allow an antibiotic called cefquinome to be used to treat cattle respiratory infections. Cefquinome is from the class of drugs known as “fourth-generation cephalosporins”—drugs that are highly valued in human medicine to treat life-threatening infections. Widespread use of cefquinome in cattle could drive human bacterial resistance to this critical class of drugs

Some animal drugs, such as cefquinome, are indiscriminately applied via injection to entire herds or flocks.  Bacteria that are constantly exposed to antibiotics develop resistance to these drugs over time.  When humans and animals get sick from resistant bacteria, the antibiotics prescribed will no longer work, resulting in life-threatening infections.

Keep Antibiotics Working is campaigning diligently to ensure that the FDA does not approve cefquinome.  While FDA is dragging its feet, another way to stop this public health threat is for drug company Schering-Plough to pull its application for the approval of cefquinome. We need your help to urge Schering-Plough CEO Fred Hassan to pull its new animal drug application for cefquinome! Please sign our petition today!

Want to read more about this important public health issue? Read the front page Washington Post coverage or explore Keep Antibiotics Working’s webpage on  cefquinome.